Everyone’s Endocannabinoid system is slightly different, you can think of it sort of like a fingerprint – unique to you.  We know that many complex chronic symptoms and even full-blown diseases are directly related to a dysfunctional Endocannabinoid system. 

ME/CFS is believed to stem from the dysregulation of multiple systems throughout the body. The symptoms are similar to those of influenza, and can include:

  • Weakness and fatigue
  • Headache
  • Tender lymph nodes
  • Joint pain
  • An inability to concentrate
  • brain fog
  • low mood
  • muscle spasms 
  • disrupted sleep patterns
  • light/temperature sensitivity 


While it’s less well documented in ME/CFS, a condition called endocannabinoids deficiency, characterized by lower amounts of naturally produced endocannabinoids in certain individuals, has been linked to fibromyalgia, making cannabis products a promising treatment.

CBD also is believed to help with your body’s homeostasis, which is keeping things like temperature, respiration, and blood flow in proper balance. Homeostasis tends to be out of balance in ME/CFS.

CBD oil is believed to be effective against pain and inflammation, and, in its pure form, it’s generally regarded as safe. Especially in light of the theory that ME/CFS is related to nerve-related inflammation, and with the wealth of evidence pointing to it being an inflammatory disease, it’s likely that CBD could help with chronic fatigue

CBD oil shows promise in treating chronic fatigue syndrome (ME/CFS) but as yet there’s no research evidence for its benefits. However, studies have demonstrated that CBD may offer help to people living with similar inflammation-related conditions, and more research specifically for ME/CFS is likely.

I have a personal interest in this as I have 2 children with M.E /CFS and use daily CBD supplements for the above symptoms with good results. I also find our CBD massage oil very beneficial. 

**Do not use during pregnancy or breastfeeding. If you take regular prescription drugs it is advisable to check with a professional before using CBD. Most drugs work in harmony with CBD but there could be some when used with CBD that could alter the efficiency of your tablets. This could make them more effective or less effective. Just check with your doctor first.**